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This is a single centre, open label, prospective, randomized study on the prophylactic effect of moderate aerobic endurance training versus relaxation training in patients with migraine.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Relaxation training | Active Comparator | Patients participate in a relaxation training program under expert guidance at least three times a week over 12 weeks. |
|
| Aerobic endurance training | Active Comparator | Patients participate in a moderate aerobic endurance training program under expert guidance three times a week over 12 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Relaxation Training | Other | Patients participate in a relaxation training program under expert guidance at least three times a week over 12 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reduction of headache days in the last 4 weeks of the 12-week training compared to baseline (4 weeks before start of the training). | 16 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Number of headache days 12 weeks after finishing the training (follow up). | 20 weeks | |
| Consumption of analgetic agents/triptans | 20 weeks | |
| Increase in aerobic capability |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Charly Gaul, MD | Department of Neurology, University of Duisburg-Essen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Neurology, University of Duisburg-Essen | Essen | 45147 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22540391 | Derived | Totzeck A, Unverzagt S, Bak M, Augst P, Diener HC, Gaul C. Aerobic endurance training versus relaxation training in patients with migraine (ARMIG): study protocol for a randomized controlled trial. Trials. 2012 Apr 27;13:46. doi: 10.1186/1745-6215-13-46. |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D012064 | Relaxation Therapy |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D001521 | Behavior Therapy |
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| Aerobic endurance Training | Other | Patients participate in a moderate aerobic endurance training program under expert guidance three times a week over 12 weeks. |
|
| 12 weeks |
| Impact on burden of disease | 20 weeks |
| Psychological Impact of Training | 20 |
| D009422 | Nervous System Diseases |
| D011613 |
| Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |