NSAIDs in Coronary Artery Disease Patients

Non-steroidal Anti-inflammatory Drugs Impair the Platelet Inhibiting Effect of Acetylsalicylic Acid in Coronary Artery Disease Patients

Introduction:

Different groups already showed in retrospective subgroup analyses, that there is an increased risk for cardiovascular events in patients on a simultaneous ASA/NSAID treatment.

Methods:

Light-Transmission aggregometry

Hypothesis:

Simultaneous administration of different NSAIDs and ASA impair the platelet inhibiting effect of ASA.

Inclusion Criteria:

• Patients on a simultaneous ASA, NSAID treatment
• > 18 years

Exclusion Criteria:

• unconsciousness, not able to consent
• reanimation, cardiac shock