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Introduction:
Different groups already showed in retrospective subgroup analyses, that there is an increased risk for cardiovascular events in patients on a simultaneous ASA/NSAID treatment.
Methods:
Light-Transmission aggregometry
Hypothesis:
Simultaneous administration of different NSAIDs and ASA impair the platelet inhibiting effect of ASA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stable CAD, ASA, NSAID | |||
| Stable CAD, ASA |
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| Measure | Description | Time Frame |
|---|---|---|
| Thromboxane-levels and light-transmission aggregometry in response to arachidonic acid | During hospital stay |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with a stable CAD undergoing coronary angiography in the Universitätsklinik Düsseldorf.
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| Name | Affiliation | Role |
|---|---|---|
| Amin Polzin, MD | Klinik für Kariologie, Pneumologie und Angiologie, Universtiätsklinikum Düsseldorf | Principal Investigator |
| Tobias Zeus, MD | Klinik für Kardiologie, Pneumologie und Angiologie | Study Chair |
| Thomas Hohlfeld, MD | Institut für Pharmakologie und Klinische Pharmakologie, Heinrich-Heine-Univerität Düsseldorf | Study Chair |
| Malte Kelm, MD | Heinrich-Heine University, Duesseldorf | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Heinrich-Heine-University | Düsseldorf | North Rhine-Westphalia | 40225 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28262342 | Derived | Achilles A, Mohring A, Dannenberg L, Piayda K, Levkau B, Hohlfeld T, Zeus T, Kelm M, Polzin A. Analgesic medication with dipyrone in patients with coronary artery disease: Relation to MACCE. Int J Cardiol. 2017 Jun 1;236:76-81. doi: 10.1016/j.ijcard.2017.02.122. Epub 2017 Feb 27. |
| Label | URL |
|---|---|
| Related Info | View source |
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