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| ID | Type | Description | Link |
|---|---|---|---|
| R01DA013444 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Drug Abuse (NIDA) | NIH |
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The investigators will randomize 300 cocaine-dependent methadone patients to 1 of 6 conditions: (a) a control group, (b) a contingency management condition that arranges a 100% probability of winning a prize with each draw and has 3 prize categories, (c) a contingency management condition that arranges a 31% probability of winning and has 3 prize categories, (d) a contingency management condition that arranges a 100% probability of winning and has 7 prize categories, (e) a contingency management condition that arranges a 31% probability of winning and has 7 prize categories, or (f) usual prize contingency management with a 50% probability of winning from 3 prize categories. Magnitudes of reinforcement will be identical across conditions, but lower overall probability conditions arrange for greater chances of winning larger magnitude prizes. The investigators expect that the new contingency management conditions will reduce cocaine use relative to the control condition, that 31% probability conditions will decrease drug use relative to 100% conditions, and that 7-prize category conditions will reduce drug use compared to 3-prize category conditions. In addition, the 31%/7-category condition is expected to be most efficacious. Results will be instrumental for further developing prize contingency management to improve outcomes of cocaine-dependent methadone patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment Group A | No Intervention | Standard Care | |
| Treatment Group B | Experimental | 100% probability of winning a prize with each draw and has 3 prize categories |
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| Treatment Group C | Experimental | 31% probability of winning and has 3 prize categories |
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| Treatment Group D | Experimental | 100% probability of winning and has 7 prize categories |
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| Treatment Group E | Experimental | 31% probability of winning and has 7 prize categories |
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| Treatment Group F | Experimental | usual prize contingency management with a 50% probability of winning from 3 prize categories |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| prize contingency management | Behavioral | Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence. |
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| Measure | Description | Time Frame |
|---|---|---|
| longest continuous period of cocaine abstinence | three months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sheila M Alessi, Ph.D. | UConn Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | United States |
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| ID | Term |
|---|---|
| D019970 | Cocaine-Related Disorders |
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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