Effect of Yoga in Reducing Chemotherapy Induced Nausea and Vomiting

Comparison of Yoga Versus Relaxation on Chemotherapy Induced Nausea and Vomiting (CINV) Outcomes Following Chemotherapy

• This randomized controlled three arm study compares the effects of a yoga intervention with jacobsons progressive muscle relaxation training and only standard of care in chemotherapy naive cancer patients.
• This study will also assess the neurophysiological correlates of nausea and vomiting and assess if effects of intervention on nausea and vomiting outcomes are mediated by changes in gastric motility (electrogastrogram) or stress arousal (cardiac autonomic function and sympathetic skin response) or self reported anxiety.

Inclusion Criteria:

• Patients with gynecologic malignancies (breast, ovary) and Lymphomas.
• Age between 30-70 years.
• Chemotherapy naïve.
• High school education.

Exclusion Criteria:

• Those with brain metastases
• Concurring medical condition likely to influence survival
• Uncontrolled diabetes and hypertension
• GI metastases, peritoneal fluid, uraemia
• Neurological disorders such as Parkinson's disease, myotonic dystrophy etc.
• GI obstruction and past H/o abdominal surgeries.
• Cognitive impairments.
• Regular participation in a behavioral intervention/yoga in the last six months