Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This will be a prospective longitudinal study describing clinical throughput metrics and patient reported quality of life outcome measures for patients undergoing Volumetric modulated arc therapy (VMAT) with and without Cone-beam computed tomography (CBCT) for head and neck carcinoma at the British Columbia Cancer Agency.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| VMAT with CBCT | Experimental | Volumetric modulated arc therapy (VMAT) with cone-beam computed tomography position (CBCT) verification |
|
| VMAT with kV-ray | Active Comparator | Volumetric modulation arc therapy (VMAT) with kV-ray position verification |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| VMAT with CBCT | Radiation | volumetric modulated arc therapy (VMAT) with cone-beam computed tomography (CBCT) position verification |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical efficiency for volumetric modulated arc therapy (VMAT) delivery | Prospective work-flow metrics describing clinical efficiency for volumetric modulated arc therapy (VMAT) delivery with and without cone-beam computed tomography (CBCT) acquisition at the BCCA, generated from time requirements for treatment verification and delivery. The time spent by the patients at each stage of radiation therapy delivery will be recorded, including; time in radiation bunker, time in immobilization frame, kV or CBCT acquisition and online correction time, and beam on time | After patient treated |
| Position verification | Summary description of position verification and online corrections for volumetric modulated arch therapy (VMAT) delivery with and without cone-beam computed tomography (CBCT) | After patient treated |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life | European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Head and Neck Cancer (EORTC QLQ - HN35) (23) (see Appendix V) and State Trait Anxiety Index (STAI) | No time frame (ongoing) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jonn Wu, MD | British Columbia Cancer Agency | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| BC Cancer Agency - Vancouver Centre | Vancouver | British Columbia | V5Z4E6 | Canada |
Not provided
| ID | Term |
|---|---|
| D050397 | Radiotherapy, Intensity-Modulated |
| ID | Term |
|---|---|
| D020266 | Radiotherapy, Conformal |
| D011881 | Radiotherapy, Computer-Assisted |
| D011878 | Radiotherapy |
| D013812 | Therapeutics |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| VMAT with kV-ray | Radiation | Volumetric modulated arc therapy (VMAT) with kV-ray position verification |
|