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The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset sensory block than injecting the initial bolus via the perineural catheter. The study results will help define the optimal local anesthetic bolus introduction technique-needle versus catheter-for peripheral nerve blocks when placing a perineural catheter.
Specific Aim: The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset sensory block than injecting the initial bolus via the perineural catheter. The study results will help define the optimal local anesthetic bolus introduction technique-needle versus catheter-for peripheral nerve blocks when placing a perineural catheter.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Local Anesthetic Via Catheter | Active Comparator | 30mL of Lidocaine (local Anesthetic) will be injected via a perineural catheter at hour 0. |
|
| Local Anesthetic Via Needle | Active Comparator | 30mL of Lidocaine (local Anesthetic) will be injected via a needle at hour 0. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Local Anesthetic given via perineural catheter for infraclavicular nerve block. | Procedure | Patients will be randomized to receive 30mL of Lidocaine via Catheter for an infraclavicular nerve block on one side (right or left) and via needle on the other side. Sensory and strength will be tested following local anesthetic administration. |
| Measure | Description | Time Frame |
|---|---|---|
| Sensory Level | EKG pads will be positioned in the 5 major nerve distributions distal to the elbow, ensuring placement is equivalent bilaterally. The primary endpoint will be the time, in minutes, until all 5 nerve territories record > 60 mA, or 120 minutes-whichever occurs first-since 60 mA is estimated to be equivalent to a surgical incision. | 120 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Grip Strength | Evaluated using a portable isometric force dynamometer to measure the maximum voluntary isometric contraction (MVIC) of the hand/fingers. Subjects will be asked to take 2 sec to come to maximum effort, maintain this effort for 3 sec, and then relax. | 120 Minutes |
| Sensory level for individual nerves |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Brian M Ilfeld, M.D., M.S. | University of California, San Diego | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UCSD CTRI, Hillcrest | San Diego | California | 92103 | United States |
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| Local Anesthetic given via needle for infraclavicular nerve block | Procedure | Patients will be randomized to receive 30mL of Lidocaine via Catheter for an infraclavicular nerve block on one side (right or left) and via needle on the other side. Sensory and strength will be tested following local anesthetic administration. |
|
Evaluated using transcutaneous electrical stimulation (TES) in the same manner as described for the primary end point. |
| 120 Minutes |