Heart Failure With Normal Ejection Fraction (HFNEF) in Hemodialysed Patients: Beneficial Effect of Ivabradine

Heart Failure With Normal Ejection Fraction (HFNEF) in Hemodialysed Patients: Beneficial Effect of Ivabradine

Heart failure with normal ejection fraction is often under diagnosed and certainly under treated in hemodialyzed patients. Because of the benefit of reducing heart rate, ivabradine, a pure heart-rate lowering agent without effects on blood pressure, is of potential therapeutic utility.

Inclusion Criteria:

• hemodialyzed patients
• signs and symptoms of heart failure with normal ejection fraction
• sinus rhythm

Exclusion Criteria:

• atrial fibrillation/atrial flutter
• valvular heart disease
• unstable angina
• hospitalization for heart failure prior 3 months