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| Name | Class |
|---|---|
| A.T. Still University of Health Sciences | OTHER |
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The specific aim is to determine if there are patterns of temperature differences in the abdominal and back regions of individuals with partial/focal onset epilepsy as compared to a non-epileptic control group. The hypothesis is that individuals with partial/focal onset epilepsy will have colder recorded temperatures in the abdominal area than individuals in a matched control group.
The concept of "Abdominal Epilepsy" has been described in the neurology literature. The present study seeks to amplify understanding of this clinical entity by measuring abdominal area and low back skin temperature changes which may be affected through the function of the abdominal ganglia, specifically the Celiac, Superior Mesenteric and Inferior Mesenteric Ganglia.
This not an intervention study. It is study comparing abdominal area and low back skin temperature in individuals with the Partial/Focal Onset Epilepsy with a match control group of individuals with no epilepsy history. The implications of the outcome of the finding any significant temperature changes between the experimental and control groups is great enough to warrant the highest level of scientific scrutiny that this registration permits.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Epilepsy Group | Individuals diagnosed with Partial/Focal Onset Epilepsy ICD9CM 345.4 and/or 345.5 | ||
| Control Group | Individuals who do not have the diagnosis of Epilepsy and have no history of seizure disorders |
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| Measure | Description | Time Frame |
|---|---|---|
| Thermographic imagery of the abdominal area | State of the art thermographic imagery of the imagery of the abdominal area from the xyphoid bone to just above the public symphysis. It is hypothesized that the average temperature for the experimental group will be lower than the control group. Since this is a measurement or diagnostic study using thermographic imagery, there is no health risk to the subjects. | Each experimental subject and each control subject will be seen once for the administration of the thermography imagery |
| Measure | Description | Time Frame |
|---|---|---|
| low back thermography imagery | Besides abdominal area will also do theographic imagery of low back of subjects because of the possibility of dermatomal skin area temperature changes possibly related the "Abdominal Epilepsy" dysfunction of the Celiac, Superior Mesenteric and Inferior Mesenteric Ganglia | one time for thermographic imagery |
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Inclusion Criteria Experimental Group:
Exclusion Criteria Experimental Group:
Pregnancy
Recent trauma such as motor vehicle accident or injury to the musculoskeletal system
Currently on medication, other than for epilepsy which may affect autonomic nervous system function, e.g. Glaucoma medication
If diagnosed with a condition which could affect abdominal area neurophysiologic functions.
Inclusion criteria Control group:
Exclusion Criteria Control group:
Pregnancy
Recent trauma such as motor vehicle accident or injury to the musculoskeletal system
Currently on medication, other than for epilepsy which may affect autonomic nervous system function, e.g. Glaucoma medication
If diagnosed with a condition which could affect abdominal area neurophysiologic functions.
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50 individual with diagnosis of focal onset epilepsy 50 normal matched control subjects
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| Name | Affiliation | Role |
|---|---|---|
| Hollis H King, DO, PhD | AT Still University of Health Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Epilepsy Foundation of Florida | Miami | Florida | 33126 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 11805256 | Background | Henkel A, Noachtar S, Pfander M, Luders HO. The localizing value of the abdominal aura and its evolution: a study in focal epilepsies. Neurology. 2002 Jan 22;58(2):271-6. doi: 10.1212/wnl.58.2.271. | |
| 15833692 | Background | Zinkin NT, Peppercorn MA. Abdominal epilepsy. Best Pract Res Clin Gastroenterol. 2005 Apr;19(2):263-74. doi: 10.1016/j.bpg.2004.10.001. |
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| ID | Term |
|---|---|
| D004828 | Epilepsies, Partial |
| D004827 | Epilepsy |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| side thermography imagery |
To capture possible dermatomal skin temperature effects will do thermographic imagery of the side or lateral aspect of the subjects. |
| one time for thermographic imagery |