Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload

Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload Patients With β-Thalassemia and Intermediate Thalassemia in Bandarabbas

Thalassemic patients often suffer from iron overload due to frequent blood transfusion. Oral iron chelators reduce iron overload in transfusion dependent patients. The aim of this study is to compare the efficacy and safety of osveral and desferal in transfusional iron overload patients with β-Thalassemia and intermediate Thalassemia in Bandarabbas.

This is a double blinded randomized controlled trial on Efficacy and safety of Osveral and Desferal in thalassemic patients.

Inclusion Criteria:

• Confirmed intermedia or major thalassemia
• More then 2 years old
• Serum Ferritin level > 1000
• Normal Creatinine and Complete Blood Count (CBC)

Exclusion Criteria:

• HCV, HBV or HIV positive patients