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Studies have shown that more than 30% of the overall acute decompensated heart failure (ADHF) patients develop renal dysfunction.
Several studies have tried to find a correlation between hemodynamic Parameters (blood pressure , heart rate, central venous pressure CVP) and worsening of renal function in acute decompensated heart failure patients.
Results showed that there were no correlation between baseline hemodynamics or change in hemodynamics and worsening of renal function.
Another study showed that intra-abdominal pressure (IAP) measuring was a better corollary to renal failure status then measuring cardiovascular hemodynamics using pulmonary artery catheterization in ADHF patients.. An increased IAP was associated with worse renal function and that level of IAP far below abdominal compartment syndrome may adversely affect renal function in patients with ADHF.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Acute CHF patients | Acute CHF patients with BARD Intra-abdominal pressure monitors in ICU |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BARD® Intra-abdominal Pressure monitor | Device | monitor linked to foley catheter that is able to measure pressure inside bladder |
|
| Measure | Description | Time Frame |
|---|---|---|
| High intraabdominal pressure and effect on renal function | IAP measurements will be recorded concomitantly with renal indices. Correlations will be made in regard to pressure measurements and worsening renal function. | from admission (baseline) until 72 hours later |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of diuretics use on intrabdominal pressure | Early initiation of diuretics in acute heart failure improvement correlating with decreasing IAP measurements. | 3 days from admission |
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Inclusion Criteria:
Exclusion Criteria:
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The studied group will consist of patients admitted to the ICU (intensive care unit) or CCU(coronary care ubnit) with evidence of ADHF. We aim in our study to find out if there is a linear relationship between worsening of renal function , IAP ,hemodynamic (CVP) and blood chemical measurements
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| Name | Affiliation | Role |
|---|---|---|
| Suzanne El-Sayegh, MD | Staten Island University Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Staten Island University Hospital | Staten Island | New York | 10305 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17377769 | Background | Cheatham ML, Malbrain ML, Kirkpatrick A, Sugrue M, Parr M, De Waele J, Balogh Z, Leppaniemi A, Olvera C, Ivatury R, D'Amours S, Wendon J, Hillman K, Wilmer A. Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations. Intensive Care Med. 2007 Jun;33(6):951-62. doi: 10.1007/s00134-007-0592-4. Epub 2007 Mar 22. | |
| 9583702 |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| Background |
| Cheatham ML, Safcsak K. Intraabdominal pressure: a revised method for measurement. J Am Coll Surg. 1998 May;186(5):594-5. doi: 10.1016/s1072-7515(98)00122-7. No abstract available. |
| 16708717 | Background | Geisberg C, Butler J. Addressing the challenges of cardiorenal syndrome. Cleve Clin J Med. 2006 May;73(5):485-91. doi: 10.3949/ccjm.73.5.485. |
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |