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This study is ancillary. Participants will be recruited as part of a separate clinical trial on effects of two intensive behavioral training programs that evaluates feasibility and efficacy of a behavioral treatment that includes mindfulness techniques (MT) in comparison to traditional behavioral therapy (CBT) for smoking cessation. The investigators propose to compare the effect of MT to that of traditional CBT on a physiological marker of stress, salivary cortisol concentration, and physiological responses to smoking cues in tobacco smokers. The investigators will use electrophysiological reactivity to smoking cues in the form of audio recordings of personalized scripts describing the scenarios associated with the strongest urges to smoke that will provide a physiological validation to a behavioral intervention. The investigators will also explore correlations between these biological markers and self report of stress, craving and negative affect to supplement self report and behavioral outcome measures with biological and physiological markers to represent improvement attributed to the intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Traditional behavioral intervention | Active Comparator |
| |
| Mindfulness behavioral intervention | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT) | Behavioral | 60 smokers will enter a separate 4 wk group sessions trial that evaluates efficacy of MT in comparison to CBT for smoking cessation. During the parent study, participants will receive bi-weekly sessions of either MT or CBT, for 4 weeks and to set a quit date at the end of the 2nd week. In this context, we will examine participants at two points:
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| Measure | Description | Time Frame |
|---|---|---|
| physiologic reactivity (skin conductance, Heart rate, electromyogram, cortisol measures) to smoking cues in recently abstinent tobacco smokers |
| It will be measured twice during the study: before treatment (baseline at week 0) and an average of 7 days after treatment (end point assessment) |
| Measure | Description | Time Frame |
|---|---|---|
| self reported of cue-induced negative affect, craving, and stress in recently abstinent tobacco smokers | It will be measured twice at the baseline assessment (before and after script driven imagery) and twice at the end point assessment (before and after script driven imagery) |
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Inclusion Criteria:
Inclusion Criteria for the entire trial:
Inclusion criteria for the physiological assessment:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gladys N Pachas, MD | Massachusetts General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Center For Addiction Medicine-Massachusetts General Hospital | Boston | Massachusetts | 02478 | United States |
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