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| Name | Class |
|---|---|
| Eisai Inc. | INDUSTRY |
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The change of Modified ADAS-cog score from the baseline to post-intervention will be compared between the cognitive intervention group and wait list control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group cognitive intervention | Active Comparator | The cognitive training will be administered twice a week for 12 weeks, located in hospital-based outpatient memory clinics. Each session will last approximately 90 minutes. The cognitive training programs will be offered in group sessions consisted of 5 participants. |
|
| Home-based cognitive intervention | Active Comparator | The participants will do their homework for 30 minutes every business days for 12 weeks. |
|
| Wait list Control | No Intervention | They will participate in cognitive intervention after ending this study. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| group cognitive intervention | Other | The cognitive training will be administered twice a week for 12 weeks, located in hospital-based outpatient memory clinics. Each session will last approximately 90 minutes. The cognitive training programs will be offered in group sessions consisted of 5 participants. |
| Measure | Description | Time Frame |
|---|---|---|
| Modified Alzheimer's Disease Assessment Scale-Cognitive subscale(ADAS-cog) | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| story recall test | postintervention, 12 weeks follow-up, and 24 weeks follow-up | |
| Digit span forward and backward | postintervention, 12 weeks follow-up, and 24 weeks follow-up | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Seong H Choi, MD, PhD | Inha University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Korea University Medical College | Ansan | South Korea | ||||
| Soonchunhyang University Hospital |
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| Home-based cognitive intervention | Other | The participants will do their paper and pencil homework for 30 minutes every business days for 12 weeks. |
|
| Word fluency test |
| postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| color-word stroop test | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Digit symbol test | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| prospective memory test | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Mini-Mental State Examination | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| CDR-SB | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| K-AD8 | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| PRMQ | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| MMQ-Strategy | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| QOL-AD | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Geriatric Depression Scale-short form | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Bayer ADL | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| CGA-NPI | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Subjective cognitive assessment | postintervention, 12 weeks follow-up, and 24 weeks follow-up |
| Bucheon-si |
| 420-767 |
| South Korea |
| Bucheon St. Mary's Hospital, the Catholic University of Korea | Bucheon-si | South Korea |
| Donga University Hospital | Busan | 602-715 | South Korea |
| Pusan National University Hospital | Busan | South Korea |
| Daejun Eulji University Hopistal | Daejun | 302-799 | South Korea |
| Myongji Hospital | Goyang | 412-270 | South Korea |
| NHIC Ilsan Hospital | Goyang | South Korea |
| Inha Univeristy Hospital | Incheon | 400-711 | South Korea |
| Jeju National University Hospital | Jeju City | South Korea |
| Maryknoll Hospital | Pusan | South Korea |
| Bobath Memorial Hospital | Seongnam | South Korea |
| Sungkyunkwan University, Samsung Seoul Hospital | Seoul | 135-710 | South Korea |
| Asan Medical Center, Psychiatry | Seoul | 431-060 | South Korea |
| Inje University Sanggye Paik Hospital | Seoul | South Korea |
| Konkuk University Medical Cener | Seoul | South Korea |
| Ajou University Hospital | Suwon | South Korea |
| Hyoja Geriatric Hospital | Yongin | South Korea |
| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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