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| Name | Class |
|---|---|
| Baxter Healthcare Corporation | INDUSTRY |
This is a preliminary study to determine the safety and efficacy of intravenous immune globulin in treating Spinocerebellar Ataxia. The investigators aim to assess changes in clinical measures of disease severity before and after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IVIG | Experimental | Intravenous Immune Globulin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| IVIG | Biological | Intravenous Immune Globulin |
|
| Measure | Description | Time Frame |
|---|---|---|
| Scale for the Assessment and Rating of Ataxia | participants will be followed for approximately 4 months |
| Measure | Description | Time Frame |
|---|---|---|
| Timed 25 foot walk | participants will be followed for approximately 4 months | |
| Clinical Global impression | participants will be followed for approximately 4 months | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Theresa Zesiewicz, MD | University of South Florida | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of South Florida | Tampa | Florida | 33612 | United States |
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| ID | Term |
|---|---|
| D020754 | Spinocerebellar Ataxias |
| ID | Term |
|---|---|
| D002524 | Cerebellar Ataxia |
| D002526 | Cerebellar Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D016756 | Immunoglobulins, Intravenous |
| ID | Term |
|---|---|
| D007074 | Immunoglobulin G |
| D007132 | Immunoglobulin Isotypes |
| D000906 | Antibodies |
| D007136 | Immunoglobulins |
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| Biodex Balance SD |
| participants will be followed for approximately 4 months |
| Gait Rite Mat | participants will be followed for approximately 4 months |
| Berg balance scale | participants will be followed for approximately 4 months |
| Complete Metabolic Panel | participants will be followed for approximately 4 months |
| Complete Blood Count | participants will be followed for approximately 4 months |
| D009422 |
| Nervous System Diseases |
| D013132 | Spinocerebellar Degenerations |
| D013118 | Spinal Cord Diseases |
| D020271 | Heredodegenerative Disorders, Nervous System |
| D019636 | Neurodegenerative Diseases |
| D001259 | Ataxia |
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D007162 |
| Immunoproteins |
| D001798 | Blood Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D012712 | Serum Globulins |
| D005916 | Globulins |