Not provided
Not provided
Not provided
Not provided
Not provided
Lack of patients for recruitment
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| The Fertility Clinic Braedstrup Hospital | UNKNOWN |
| Herlev Hospital | OTHER |
| Odense University Hospital | OTHER |
| Trianglen Fertility Clinic |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The primary purpose of the investigation is to identify differences in embryo development after follicle stimulation with two different gonadotrophins.
So far the assessment of the development potential of the single embryo has been limited by the vulnerability of the embryos when exposed to fluctuations in temperature and CO2 levels.
Thus embryos can only be allowed to leave incubators for a very limited time period.
However, with the development of time-lapse systems for clinical use it is possible to make continuous time-lapse recordings of embryos while they are in a safe incubator environment.
The embryos are not compromised, but the entire embryonic development can still be seen, and will subsequently provide new and essential information on the competence of the single embryo.
Based on the above it is expected that the probability of selecting the most viable and competent embryo is increased, which, in turn, will increase the success rate for couples seeking infertility treatment.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| urine-derived FSH | Active Comparator | Follicle stimulating hormone |
|
| recombinant FSH | Active Comparator | Follicle stimulation hormone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HP-HMG | Drug | 100 - 300 IU for stimulation of women in ART treatment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of Top Quality Embryos day 2 | The oocytes are inseminated and loaded to the time-lapse instrument and cultured for two days. The embryo developemnt are followed at the movie and the embryos are scored according to a standard scoring criteria at 44 h after insemination | 44 h after insemination |
| Measure | Description | Time Frame |
|---|---|---|
| Implantation rate | The pregnancy is verified by a blood sample two weeks after embryo transfer and the number of embryos implanted are verified by ultrasound scanning five weeks after embryo transfer. | 5 weeks after embryo transfer |
Not provided
Inclusion Criteria:
Participants(heterosexuals, lesbian couples and single women) must sign a document of informed consent
Exclusion Criteria:
PCO
- Endometriosis as primary diagnosis
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Inge Agerholm, Phd | IVF clinic Braedstrup | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The fertility clinic | Brædstrup | 8740 | Denmark |
Not provided
| ID | Term |
|---|---|
| C571801 | follitropin alfa |
Not provided
Not provided
Not provided
| UNKNOWN |
| Aagaard Fertility Clinic | OTHER |
| Ferring Pharmaceuticals | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
| recombinant FSH | Drug | 100 -300 IU for stimulation of women in ART treatment |
|
|