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A comparative study to determine whether bed rest after embryo transfer (ET) affects on IVF (In Vitro Fertilization)outcome. This study includes 240 patients undergoing IVF treatment with donated oocytes. All the procedures of IVF, of the embryo transfer, and of the administration of medications are performed as always and there are no variations. The only highlighted procedure in this study is immediately after the embryo transfer. There are two groups: one which will rest in bed for 10 minutes after the transfer and one which will not rest after the transfer. Both procedures are common, usually depending on the habitual clinical practice of each clinic internationally. Patients from both group receive the routine post transfer instructions and treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bedrest | Active Comparator | Patients will rest in bed ten minutes after the embryo transfer. |
|
| No bed rest | Experimental | Patients will not rest after the embryo transfer. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bed rest | Behavioral | Patients will rest in bed ten minutes after the embryo transfer. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Live birth infant rate after delivery from both groups of study | Whether bed rest after embryo transfer affects the pregnancy rate in IVF treatment with oocyte donation. | 10 months |
| Measure | Description | Time Frame |
|---|---|---|
| Implantation rate | 2 months | |
| Miscarriage rate | 5 months | |
| Birth weight of live newborn infant after delivery |
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Inclusion criteria:
Exclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dr. Sharayi Gaikwad, MD | Instituto Valenciano de Infertilidad | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto Valenciano de Infertilidad | Valencia | 46117 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23755954 | Derived | Gaikwad S, Garrido N, Cobo A, Pellicer A, Remohi J. Bed rest after embryo transfer negatively affects in vitro fertilization: a randomized controlled clinical trial. Fertil Steril. 2013 Sep;100(3):729-35. doi: 10.1016/j.fertnstert.2013.05.011. Epub 2013 Jun 10. |
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| ID | Term |
|---|---|
| D001510 | Bed Rest |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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| No bedrest |
| Behavioral |
Patients will not rest in bed after the embryo transfer. |
|
| 10 months |
| Birth height of live newborn infant after delivery | 10 months |
| Cranial perimeter of live newborn infant after delivery | 10 months |
| APGAR score of live newborn infant after delivery | 10 months |