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| Name | Class |
|---|---|
| Asan Medical Center | OTHER |
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A Randomized, Open Label, Single dose, Cross-over, Phase I Trial to Investigate Safety and Pharmacokinetics of Apetrol ES and Megace® under Fed Conditions in Healthy Male Volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 : Megace 800mg - Apetrol ES 650mg - Apetrol ES 675mg | Experimental |
| |
| Group 2 : Apetrol ES 650mg - Apetrol ES 675mg -Megace 800mg | Experimental |
| |
| Group 4: Megace 800mg - Apetrol ES 675mg - Apetrol ES 650mg | Experimental |
| |
| Group 5: Apetrol ES 650mg - Megace 800mg - Apetrol ES 675mg | Experimental |
| |
| Group 3: Apetrol ES 675mg - Apetrol ES 650mg - Megace 800mg | Experimental |
| |
| Group 6 : Apetrol ES 675mg - Megace 800mg - Apetrol ES 650mg | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Apetrol ES | Drug | sequences of administered drugs |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cmax, AUClast | Day 34 |
| Measure | Description | Time Frame |
|---|---|---|
| AUCinf, Tmax, t1/2(beta) | Day 34 |
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Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asan Medical Center | Seoul | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25450470 | Derived | Kim YH, Choi HY, Jin S, Noh YH, Kim MJ, Park HJ, Lim HS, Bang K, Lee SH, Bae KS. Tolerability and pharmacokinetics of two formulations of megestrol acetate under fed conditions in healthy volunteers. Clin Ther. 2015 Feb 1;37(2):439-47. doi: 10.1016/j.clinthera.2014.09.022. Epub 2014 Oct 23. |
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