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| ID | Type | Description | Link |
|---|---|---|---|
| 16811 | Other Identifier | REB |
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Major abdominal surgeries are associated with perioperative cardiac morbidity of up to 10%.
Ischemic preconditioning may have a protective effect. The purpose of this study is to find out remote ischemic conditioning by inflating a blood pressure cuff on the arm will have a protective effect.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Arm remote preconditioning |
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| 2 | Placebo Comparator | Control group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Remote Ischemic Pre-conditioning | Procedure | Cuff placed on arm. Three 5- minute cycles of blood pressure cuff inflation: cuff is inflated to 200 mm Hg for 5 minutes followed by a 5-minute deflation (reperfusion.) |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiovascular Events: incidence of MI, TIA/stroke, death in both groups | One week |
| Measure | Description | Time Frame |
|---|---|---|
| Renal function deterioration in the first week after surgery | Baseline Creatinine levels will be compared to the highest creatinine levels noted in the first 7 days of hospitalization | One week |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ronit Lavi, MD | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| London Health Sciences Centre | London | Ontario | N6A 5W9 | Canada |
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| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Control | Procedure | Cuff placed on arm uninflated for 30 minutes. |
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