Is It Possible to Predict Pre Term Labor by Measuring Cervical Length in the Non-pregnant Uterus?

Is It Possible to Predict Pre Term Labor by Measuring Cervical Length in the Non-pregnant Uterus?

Working hypothesis and aims:

To investigate the association between cervical length in non-pregnant women, and the risk of premature birth.

The participants will be recruited from the HaEmek Medical Center delivery room registration. Women delivered between 24-37 pregnancy weeks will be allocated to the study group. The investigators will invite them 3 month or more after delivery to ultrasound examination of the cervical length. The participants in the control group will be the women whom term delivery follows by chronological manner to those in study group. Data of the cervucal length will be collected at the time of the examination.

Women will be invited to undergo an examination in Ultrasound Unit of Department of Obstetrics and Gynecology, HaEmek Medical Center.

Ultrasound examination will be performed using the Voluson E8 device, General Electric.

The cervical length,between the external and internal orifice will be measured using conventional technologies available including: Doppler, three dimensional and two dimensional ultrasound.

Inclusion Criteria:

• Nonpregnant women aged 18-40 years.
• Singelton last pregnancy.
• Last birth, spontaneous premature (24-37 week)
• Last birth at least 3 months ago.

Exclusion Criteria:

• Presence of uterine malformations.

• Sonographic pathologic findings.

• Technical failure (failed appropiate sonographic visualisation)

• Presence of fetal malformations ( in preterm delivery )

• Presence of comorbidities including diabetes, hypertension, collagen disease, thrombophilia

• Presence of risk factors for premature delivery (amniotic fluid infection,

  • cervical surgical treatments - conization, polyhydramnios, etc.).