Main Branch Versus Side Branch Ostial Lesion

Relationship Between Fractional Flow Reserve and Coronary Angiography/Intravascular Ultrasound Parameters in Ostial Lesions: Major Coronary Ostial Lesions Versus Side Branch Ostial Lesions

The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.

Angiographic evaluation for ostial lesions is reported to be inaccurate in the assessment of the functional and clinical significance of a lesion. The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.

Inclusion Criteria:

• Age 21-85
• Presence of at least one obstructive coronary artery stenosis at coronary ostium as defined by:
• Previous catheterization with any coronary ostium lesion 50% or greater
• Ability and Willingness to provide informed consent
• Ability and Willingness to perform required follow up procedures

Exclusion Criteria:

• History of coronary artery bypass graft surgery
• left main coronary ostial lesion
• significant stenosis at proximal or distal part of coronary ostium lesion
• ostial lesion related to infarcton
• Creatinine>1.6 mg/dL or GFR<30 pre-procedure per institutional standards
• Ejection fraction lower than 40%
• Known Pregnancy
• Arrhythmia
• Contrast agent allergy that cannot be adequately premedicated
• Patient not a candidate for IVUS and FFR
• Inability or unwillingness to provide informed consent
• Inability or unwillingness to perform required follow up procedures