The purpose of this study is to evaluate the efficacy of Prontosan® Wound Irrigation Solution compared with standard isotonic solution on infammation reduction and wound bed cleansing of chronic pressure or vascular leg ulcers.

Inclusion Criteria:

• Male and females aged at least 18 with Pressure ulcer stage 2-3 NPUAP (National Pressure Ulcer Advisory Panel 1989)or subcutaneous vascular ulcer with inflammation and/or biofilm and/or slough
• Braden index at baseline>=10
• Ulcer area<80 cm2
• Ability to give an informed consent

Exclusion Criteria:

• Braden index at baseline<10
• Current therapy with corticosteroids or immunosuppressor or radiotherapy
• Sensitivity to any of the components of Prontosan® Solution
• Diabetic foot ulcer
• Current use of local antiseptics on the wound bed
• Previous recruitment of another ulcer in the trial