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Our study will compare the use of continuous saphenous nerve block performed at the adductor canal in addition to Local Infiltration Analgesia (LIA) versus a Sham block in addition to LIA for total knee replacement. The investigators hypothesize that the saphenous nerve block performed at the level of the adductor canal in addition to LIA provides better pain relief than the LIA alone without significantly compromising muscle strength and physiotherapy, enabling patients to mobilize early with reduced opioid consumption and les side effects.
The investigators will enroll a total of 40 patients (20 patients will receive continuous saphenous nerve block in addition to LIA and 20 will receive the sham block and LIA). Until discharge, the investigators will record patients' pain scores, opioid consumption, side effects and physical therapy progress.
If our study proves that the continuous saphenous nerve block in addition to LIA can effectively reduce postoperative pain scores to an acceptable level with better physical therapy progress and less opioid consumption, it could be seen as a more attractive alternative to LIA alone or other traditionally used methods of postoperative pain control that compromises muscle strength and physiotherapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Saline boluses in nerve catheter | Sham Comparator | A nerve catheter will be placed in the adductor canal using saline instead of Ropivacaine for intermittent boluses. |
|
| Continuous saphenous nerve block | Active Comparator | Postoperative intermittent boluses of 15 Ml Ropivacaine 7,5 mg/Ml every 12 hours for three days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| continuous saphenous nerve block | Procedure | Postoperative intermittent boluses of 15 Ml Ropivacaine 7,5 mg/Ml every 12 hours for three days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain scores | VAS pain scores | 3 days postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Opioid consumption | 3 days postoperative | |
| physical therapy progress | 3 days postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Henning L. Andersen, M.D. | Frederiksberg Hospital | Principal Investigator |
| Dusanka Zaric, M.D., Ph.d. | Frederiksberg Hospital. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anaestesiafdelingen, Frederiksberg Hospital | Frederiksberg | 2000 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23222363 | Derived | Andersen HL, Gyrn J, Moller L, Christensen B, Zaric D. Continuous saphenous nerve block as supplement to single-dose local infiltration analgesia for postoperative pain management after total knee arthroplasty. Reg Anesth Pain Med. 2013 Mar-Apr;38(2):106-11. doi: 10.1097/AAP.0b013e31827900a9. |
| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| Saline boluses in nerve catheter | Procedure | A nerve catheter will be placed in the adductor canal using saline instead of Ropivacaine for intermittent boluses. |
|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |