Cerebral Blood Flow Effects of Resveratrol and Piperine in Humans

Effects of Resveratrol Alone or in Combination With Piperine on Cerebral Blood Flow Parameters and Cognitive Performance in Humans

Resveratrol is associated with a plethora of physiological effects in humans, including modulation of cerebral blood flow, despite apparently poor bioavailability. This study investigated whether the physiological effects of resveratrol could be affected when co-supplemented with piperine, an alkaloid which may be able to enhance the bioavailability of resveratrol.

Inclusion Criteria:

• Between the ages of 18-35 years old
• Healthy
• Non-smoker

Exclusion Criteria:

• Not proficient in English
• Taking medication or herbal supplements
• Pregnant or breast feeding
• Heavy caffeine consumer
• History of head trauma, migraines, learning difficulties, ADHD, gastrointestinal problems.
• Food allergies of intolerances