This study will examine how menthol affects smoking when menthol smokers switch to non-menthol cigarettes. Participants will smoke their preferred brand (control) or Camel Crush cigarettes, which have the ability to be menthol or non-menthol. Participants given Camel Crush cigarettes will smoke them as menthol, then non-menthol cigarettes for 15 days each. Participants will provide breath and urine samples, track cigarette usage and complete smoking topography assessments of smoking behavior.

This study will examine how menthol affects smoking behaviors and biomarker level when menthol smokers switch to non-menthol cigarettes. Participants will initially smoke their preferred brand (control) cigarettes, followed by smoking Camel Crush cigarettes, which have the ability to be menthol or non-menthol. Participants given Camel Crush cigarettes will smoke them as menthol, then non-menthol cigarettes for 15 days each. Participants will provide breath and urine samples to measure smoke exposures, track cigarette usage to establish changes in daily cigarette consumption and complete smoking topography assessments of smoking behavior, such as puff volume.

Inclusion Criteria:

• Self-report smoking daily cigarettes
• Self-report smoking menthol flavored cigarettes
• Not currently trying to quit or planning to quit in the next 2 months.
• Interested in trying a novel cigarette product and willing to smoke a non-menthol cigarette
• Self-report smoking only filtered commercially made cigarettes

Exclusion Criteria:

• Self-report drinking equal to or greater than a certain number of alcohol-containing drinks per week
• Self report using any nicotine replacement products or nicotine-containing products other than cigarettes
• Self-report substance use disorders in the last 5 years
• Self-report current Axis I psychiatric disorders
• Self-report past history of Axis I psychiatric disorders other than depression
• Self-report myocardial infarction, angina or abnormal rhythms requiring medication
• Self-report use of select medications and illicit drugs within past six months
• Females must not be currently pregnant, planning a pregnancy during the study, or currently breastfeeding/lactating
• Provide a baseline carbon monoxide (CO) reading < 10 ppm at initial session
• Inability to provide informed consent or complete any of the study tasks as determined by the Principal Investigator

Because this was a cigarette brand switching study there was no systematic assessment tool.

Participants were asked about withdrawal symptoms due to the possibility of not smoking as many cigarettes.

Attrition rate over 35 day protocol of brand switching cigarette.