Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants

The purpose of this study is to evaluate the efficacy of clarithromycin in eradication of ureaplasma urealyticum and prevention of chronic lung disease in premature infants with birthweight < 1250 g and have ureaplasma urealyticum colonization.

Inclusion Criteria:

• The babies under 1250 gram
• The babies must be appropriate for gestational age

Exclusion Criteria:

• Multiple congenital anomalies or known syndromes
• Intrauterine growth retardation with birthweight less than 10 percentile for gestational age