The Sponsor has no interest in continuing the study.

The purpose of this study is to compare the safety and efficacy of the of propofol nanoemulsion and lipid emulsion for sedation in non-invasive ambulatory procedures.

Nanoemulsion of propofol has been developed without lipid solvent in the formulation to minimize the adverse events such as pain of injection, redness, heat, phlebitis.

Inclusion Criteria:

• Lumbar Puncture or Myelogram
• Peripheral Intravenous access available in the veins on the dorsal region of the hand
• The informed consent signed by the legal responsible of the child allowing the participation in the study

Exclusion Criteria:

• Relative or absolute contraindications use of propofol and excipients
• Contraindications to the patient undergo general anesthesia or sedation with drug
• Allergy derived from egg or soy
• Use of pre-medication
• Patient receiving psychotropic drugs
• Use of opioid within 24 hours
• The responsible for the children unable to decide for his participation
• The severity of the condition wich compromises vital functions such as ventilation and hemodynamic balance
• Liver cancer which compromises its function
• Changes in the blood tests
• Others comorbidities in the investigator opinion