Autologous Bone Marrow Stem Cell Transplantation in Patients With Spinal Cord Injury

Phase 1 Study of Autologous Bone Marrow Stem Cell Transplantation in Patients With Spinal Cord Injury

This research investigates the use of autologous bone marrow stem cells in patients with spinal cord injury.

The aim of this study is to evaluate autologous bone marrow stem cells transplantation as a safe and potentially beneficial treatment for patients with spinal cord injury.

Inclusion Criteria:

• Age between 18 and 50 years old
• Traumatic spinal cord injury at the thoracic or lumbar level
• Classification Frankel A
• Indication for spinal surgery for traumatic lesions of bone

Exclusion Criteria:

• Section of the spinal anatomy
• Open injuries
• Active infectious diseases
• Terminal patients
• Neurodegenerative diseases
• Primary hematologic diseases
• Bone reflecting increased risk for spinal puncture
• Coagulopathies
• Hepatic dysfunction
• Pregnancy
• Other medical complications that contraindicate surgery, including major respiratory complications
• Participation in another clinical trial
• Use of metal implants close to vascular structures (such as cardiac pacemaker or prosthesis) that contraindicate MRI