Fluid Collections Management in Severe Acute Pancreatitis

Management of Sterile Fluid Collections in Patients With Severe Acute Pancreatitis:a Randomized Controlled Trial

Acute fluid collections is common in patients with severe acute pancreatitis (SAP). But the treatment for this is controversial. In this study, the investigators aim to evaluate the different effects of three different treatment protocols which is repeated aspiration, continuous catheter drainage and conservative treatment. The investigators suppose repeated aspiration could not only solve acute fluid collections, but also lower the rate of pancreatic infection.

Inclusion Criteria:

• Symptoms and signs of acute pancreatitis according to Atlanta criteria and if pancreatic or/and peripancreatic fluid collections were confirmed by ultrasound and computed tomography examination
• CT density < 30Hu
• Within 7 days from the onset of the disease
• Available approach for percutaneous penetrate

Exclusion Criteria:

• Pregnant pancreatitis
• Receiving surgery or aspiration before;need of early surgery
• Infected fluid collection