Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU)

Normal Oxygenation Maintenance in Intensive Care Unit: Randomized Controlled Trial

Oxygen administration is a common practice in intensive care units, although concern is growing about oxygen toxicity. The aim of the study is to access whether a rigorous maintenance of a state of normal oxygenation in critically ill patients could obtain better outcomes, such as mortality, infections and organ failures, in comparison to conventional oxygen therapy practice.

Inclusion Criteria:

• all patients admitted in a post-operative and medical intensive care unit with expected admission of at least three days. Informed consensus as soon as possible

Exclusion Criteria:

• minority
• patient discharged from ICU and successively re-admitted
• patient enrolled in other studies
• expected survival shorter than 24 hours