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| Name | Class |
|---|---|
| Biotronik SE & Co. KG | INDUSTRY |
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The potassium value is important to prevent cardiac arrhythmias and sudden cardiac death. In patients with renal failure, the potassium value is not stable and tends to raise. Until now there are no data available if the potassium value has a circadian rhythm and if there are individual changes from day to day.
Potassium and cystatin c is measured every 2 hours during 24 hours, twice. There are two groups of patients: Patients with eGFR < 60 ml/min and patients with eGFR > 60 ml/min
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy group | 15 persons with normal renal function |
| |
| Renal failure | 15 persons with renal failure (GFR < 60 ml/min) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blood withdrawal | Procedure | blood withdrawal every 2 hours during 24 hours |
|
| Measure | Description | Time Frame |
|---|---|---|
| Potassium rhythm | 15 persons with normal renal function are hospitalized for 24 hours. Blood samples are taken every 2 hours in order to investigate the potassium value. It is repeated with 5 persons after 2 days, with 5 persons after 4 and with 5 persons after 6 days. | twice in 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Potassium value in renal failure | 15 persons with renal failure (GFR < 60 ml/min) are hospitalized for 24 hours. Blood samples are taken every 2 hours in order to investigate the potassium value It is repeated with 5 persons after 2 days, with 5 persons after 4 and with 5 persons after 6 days. | twice in 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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healthy persons compared to patients with renal failure
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| Name | Affiliation | Role |
|---|---|---|
| Roland E. Schmieder, MD | Department of Nephrology and Hypertension, University of Erlangen-Nürnberg Medical School | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Research Unit, Department of Nephrology and Hypertension, University of Erlangen-Nürnberg | Erlangen | 91054 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24990164 | Result | Schmidt ST, Ditting T, Deutsch B, Schutte R, Friedrich S, Kistner I, Ott C, Raff U, Veelken R, Schmieder RE. Circadian rhythm and day to day variability of serum potassium concentration: a pilot study. J Nephrol. 2015 Apr;28(2):165-72. doi: 10.1007/s40620-014-0115-7. Epub 2014 Jul 3. |
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| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D016757 | Death, Sudden, Cardiac |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| D006323 | Heart Arrest |
| D003645 | Death, Sudden |
| D003643 | Death |