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The aim is to study the effect of milk versus cheese on fecal fat excretion and blood lipids. To do this, a randomized crossover intervention study with 3 14-day periods (control diet, milk diet, cheese diet) will be conducted in 16 young males. Fasting blood samples will be collected before and after each period, and fecal samples will be collected for the last 5 days in each period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control diet | Experimental | Diet without dairy products |
|
| Milk diet | Experimental | Diet with a high content of milk |
|
| Cheese diet | Experimental | Diet with a high content of cheese |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dietary intervention (without dairy products) | Other | Control diet without dairy products |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Fecal fat excretion | Total excretion of fecal fat (grams/day)avaraged over five days | During day 10-14 in each period |
| Measure | Description | Time Frame |
|---|---|---|
| Total, HDL and LDL cholesterol | Day 1 and 14 in each period | |
| Triglycerides | Day 1 and 14 in each period | |
| Appetite sensation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Arne Astrup, Dr med | University of Copenhagen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Human Nutrition, University of Copenhagen | Frederiksberg C | 1958 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24622806 | Derived | Soerensen KV, Thorning TK, Astrup A, Kristensen M, Lorenzen JK. Effect of dairy calcium from cheese and milk on fecal fat excretion, blood lipids, and appetite in young men. Am J Clin Nutr. 2014 May;99(5):984-91. doi: 10.3945/ajcn.113.077735. Epub 2014 Mar 12. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D006949 | Hyperlipidemias |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D004035 | Diet Therapy |
| ID | Term |
|---|---|
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
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| Dietary intervention (high milk content) |
| Other |
Diet with a high content of milk (~1200 mg Ca/d from milk) |
|
| Dietary intervention (high cheese content) | Other | Diet with a high content of cheese (~1200 mg Ca/d from cheese) |
|
| Assessed on day 1, 8 and 14 in each period |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |