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enrollment of patients insufficient
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Postoperative delirium is common in the elderly and is associated with a significant increase in mortality, complications, length of hospital stay and admission in long care facility. Several interventions have proved their effectiveness to prevent it but their combination within a multifaceted intervention needs to be assessed using rigorous methodology based on randomized study design. CONFUCIUS trial aims to measure the impact of a multifaceted program on the prevention of postoperative delirium in elderly.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| multifaceted prevention program | Experimental |
| |
| usual care | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Multifaceted prevention program HELP(Hospital Elder Life Program) | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative delirium rate within 7 days after surgery | 7 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Mean delirium intensity within 7 days after surgery | 7 days after surgery | |
| Length of hospital stay | Hospital discharge | |
| Postoperative complications 30 days after surgery incidence |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pierre KROLAK-SALMON, Pr | Hospices Civils de Lyon- Hôpital des Charpennes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon-Hôpital des Charpennes | Villeurbanne | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21592324 | Derived | Mouchoux C, Rippert P, Duclos A, Fassier T, Bonnefoy M, Comte B, Heitz D, Colin C, Krolak-Salmon P. Impact of a multifaceted program to prevent postoperative delirium in the elderly: the CONFUCIUS stepped wedge protocol. BMC Geriatr. 2011 May 18;11:25. doi: 10.1186/1471-2318-11-25. |
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| ID | Term |
|---|---|
| D000071257 | Emergence Delirium |
| ID | Term |
|---|---|
| D003693 | Delirium |
| D003221 | Confusion |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
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|
| 30 days after surgery |
| Mortality 6 months after surgery | 6 months after surgery |
| Feasibility of the multidisciplinary prevention program | 24 months |
| D009422 |
| Nervous System Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |