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Comparison of bone mineral loss in prostate cancer patients who is receiving GnRH agonist and -plus anti-androgen agent
MC MD
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Total of 250 prostate cancer patients receiving GnRH agonist | ||
| B | Total of 250 prostate cancer patients receiving GnRH agonist plus anti-androgen agent |
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| Measure | Description | Time Frame |
|---|---|---|
| comparison of bone density before and after hormone therapy | 1 year | |
| comparison of bone density between GnRH agonist alone vs. CAB group | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| correlation between osteoporosis risk factors such as age, weight, history of smoke, history of alcohol and bone density value | 1 year | |
| correlation between osteoporosis risk factors such as age, weight, history of smoke, history of alcohol and bone density value before and after hormone therapy |
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Inclusion Criteria:
Exclusion Criteria:
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Prostate cancer patients who is receiving GnRH agonist and -plus anti-androgen agent
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| Name | Affiliation | Role |
|---|---|---|
| Joon Woo Bahn | AstraZeneca Korea | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Seongnam-si | Gyeonggi-do | South Korea | |||
| Research Site |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28262724 | Derived | Kim SH, Joung JY, Kim S, Rha KH, Kim HG, Kwak C, Lee JY, Jeon SS, Hong SK, Jeong H, Jo MK, You D, Jeong IG, Hong JH, Kim CS. Comparison of bone mineral loss by combined androgen block agonist versus GnRH in patients with prostate cancer: A 12 month-prospective observational study. Sci Rep. 2017 Mar 6;7:39562. doi: 10.1038/srep39562. |
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| 1 year |
| 1year comparison of FRAX score before and after hormonal therapy | 1 year |
| Seoul |
| South Korea |
| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
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