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| Name | Class |
|---|---|
| University of Reading | OTHER |
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The purpose of this study is to determine the effects of prebiotic B-GOS on the immune function, metabolism and gut microbiota of elderly people
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MDn | Placebo Comparator | Maltodextrin |
|
| B-GOS | Active Comparator | Prebiotic |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bi2muno® GOS | Dietary Supplement | 5.5g/day for 10 weeks |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Effect of B-GOS on immunity by measuring various inflammatory/immune biomarkers | 12 months | |
| Effect of B-GOS on the faecal microbiota composition of elderly persons | 12 months | |
| Effect of aging on body metabolites using NMR | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of B-GOS on gut permeability | 12 months | |
| Weekly assessment of stools and gastrointestinal symptoms | 8 months |
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Inclusion Criteria:
Exclusion Criteria:
Head, Ears, Eyes, Nose and Throat Dermatological/Connective tissue Coeliac disease Neurological Lymphatic Urogenital/Rectal Gastroenterological Abdominal Respiratory Cardiovascular Incontinence
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| Name | Affiliation | Role |
|---|---|---|
| Glenn Gibson, PhD | University of Reading, United Kingdom | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Reading | Reading | Berkshire | United Kingdom |
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| ID | Term |
|---|---|
| C072242 | 4'-galactooligosaccharide |
| C008315 | maltodextrin |
| D003912 | Dextrins |
| ID | Term |
|---|---|
| D013213 | Starch |
| D005936 | Glucans |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 |
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| Maltodextrin | Dietary Supplement | 5.5g daily for 10 weeks |
|
|
| Macromolecular Substances |
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D011134 | Polysaccharides |