Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly Treatment

Effects of Physiologic Growth Hormone Administration on Echocardiographic Parameters in Subjects With Growth Hormone Deficiency Following Cure of Acromegaly

The purpose of this research study is to study the effects of growth hormone (GH) replacement on the heart. The investigators will study these effects in people who have been cured of acromegaly and then have developed growth hormone deficiency (GHD, not enough growth hormone).

Inclusion Criteria:

• age 18-75
• history of acromegaly with biochemical cure
• growth hormone deficiency

Exclusion Criteria:

• untreated thyroid disease within the past 3 months
• untreated adrenal insufficiency within the past 3 months
• uncontrolled hypertension
• congestive heart failure
• gonadal steroid therapy within the past 3 months
• pregnancy or nursing