The purpose of this study is to assess blood levels of Ceftaroline fosamil in children.

To characterize single dose pharmacokinetics of Ceftaroline fosamil in children.

Inclusion Criteria:

Subjects must meet the following inclusion criteria:

• Male or female children with ages from birth to younger than 12 years
• Hospitalized and receiving systemic antibiotic therapy for treatment of a suspected or confirmed infection
• Sufficient intravascular access
• Negative urine pregnancy test
• Written informed consent from parent(s)and verbal informed assent from subject

Exclusion Criteria:

Subjects must NOT meet any of the following exclusion criteria:

• History of any hypersensitivity or allergic reaction to any β-lactam antimicrobial
• Past or current history of epilepsy or seizure disorder
• Moderate or severe renal impairment
• If female, currently pregnant or nursing
• Aspartate aminotransferase, alanine aminotransferase, or total bilirubin level > 3 times upper limit of normal
• Any condition that would make the subject, in the opinion of the Investigator, unsuitable for the study
• Use of probenecid within 3 days prior to dosing
• Receipt of a blood transfusion during the 24-hour period before enrollment