Colistin Versus Colistin Plus Fosfomycin for Infections Caused by MDR Acinetobacter Baumannii

Colistin Plus Fosfomycin in Multi-Drug Resistant Acinetobacter Baumannii

In Siriraj Hospital, colistin alone for treatment of MDR A. baumannii contributed to mortality 45% Fosfomycin is an antimicrobial which has activity against gram-negative bacterial including MDR A. baumannii In this study, we compare the clinical and microbiologicalresponse of colistin alone versus colistin plus fosfomycin in treatment of A. baumannii infected patients

Inclusion criteria

• Age> 18 years
• Hospitalized to Siriraj Hospital
• Infected caused by A. baumannii
• Need Colistin treatment

Exclusion criteria

• Pregnancy or Lactating mother
• Colistin or Fosfomycin Allergy
• Patients who have severe abnormal renal or liver function

Inclusion Criteria:

• Age> 18 years
• Hospitalized to Siriraj Hospital
• Infected caused by A. baumannii
• Need Colistin treatment

Exclusion criteria:

• Pregnancy or Lactating mother
• Colistin or Fosfomycin Allergy
• Patients who have severe abnormal renal or liver function