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| Name | Class |
|---|---|
| Hebrew University of Jerusalem | OTHER |
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The purpose of this study is to investigate the role of a one-time intranasal administration of the oxytocin, vasopressin, or placebo on prosocial decision making such as cooperation and altruism in a healthy population of student controls.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vasopressin | Experimental | vasopressin condition |
|
| oxytocin | Experimental | oxytocin condition (syntocinon) |
|
| placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxytocin | Drug | one-time intranasal administration, 24 International Units, 5 puffs for each nostril |
|
| Measure | Description | Time Frame |
|---|---|---|
| allocations of monetary units | Participants will make decisions regarding the allocation of monetary units between themselves and other participants. We will measure the quantity of monetary units kept for themselves vs. given to other participants | approximately 45 minutes after intranasal administration of vasopressin, oxytocin, or placebo |
| Measure | Description | Time Frame |
|---|---|---|
| mood as measured via the visual analog scale | approximately one hour and fifteen minutes after administration of oxytocin, vasopressin or placebo |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| David Mankuta, MD | Contact | 972-2-6776484 | mankutad@gmail.com | |
| Salomon Israel, MA | Contact | 972-524789754 | salomon.israel@mail.huji.ac.il |
| Name | Affiliation | Role |
|---|---|---|
| David Mankuta, MD | Hadassah University Medical Organization | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hadassah University Medical Organization | Recruiting | Jerusalem | Jerusalem | Israel |
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| ID | Term |
|---|---|
| D003919 | Diabetes Insipidus |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| ID | Term |
|---|---|
| D010121 | Oxytocin |
| D001127 | Arginine Vasopressin |
| ID | Term |
|---|---|
| D010909 | Pituitary Hormones, Posterior |
| D010907 | Pituitary Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
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| Arginine Vasopressin | Drug | one-time intranasal administration, 20 International Units, 5 puffs in each nostril |
|
| placebo | Drug | contains all the ingredients as in the oxytocin and vasopressin conditions, save for the active ingredient, one time intranasal administration, 5 puffs in each nostril |
|
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D010900 | Pituitary Diseases |
| D004700 | Endocrine System Diseases |
| D006730 |
| Hormones, Hormone Substitutes, and Hormone Antagonists |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D014667 | Vasopressins |
| D009479 | Neuropeptides |
| D009842 | Oligopeptides |
| D009419 | Nerve Tissue Proteins |
| D011506 | Proteins |