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Constipation following elective Caesarean sections (CS) is a common problem experienced by up to 50% of patients (1). The causes for this are multifactorial and include manipulation of the bowel during surgery, immobilisation and opiate based anaesthetic and analgesic techniques. To try to alleviate the problem of postoperative constipation, some anaesthetists prescribe postoperative lactulose in addition to postoperative analgesia, although no data exists that shows whether this has any beneficial effect on postoperative constipation.
1. Short term morbidity associated with Caesarean delivery. Hillan EM. Birth. 19 (4): 190-4).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lactulose group | Experimental | Group receives 48 hours of lactulose post Caesarean section. |
|
| Non-lactulose group | No Intervention | Group receives no lactulose post Caesarean section. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lactulose | Drug | Lactulose liquid. 15mls twice daily |
|
| Measure | Description | Time Frame |
|---|---|---|
| Time in hours to passage of first stool post Caesarean Section. | Time (hours) to first bowel motion post elective LSCS betwwen Lactulose and non-Lactulose groups. | First 5 days post Caesarean section. |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of abdominal pain between lactulose and non-lactulose groups. | Frequency of abdominal pain between lactulose and non-lactulose groups post Caesarean Section. | First 5 days post Caesarean section. |
| Frequency of nausea and vomiting between lactulose and non-lactulose groups |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anthony Davis, MBCHB | Contact | anthonydavis@nhs.net |
| Name | Affiliation | Role |
|---|---|---|
| Anthony Davis, MBCHB | NHS Fife | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Forth Park Hospital | Kirkcaldy | Fife | EH4 1QH | United Kingdom |
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| ID | Term |
|---|---|
| D003248 | Constipation |
| D015746 | Abdominal Pain |
| D009325 | Nausea |
| D014839 | Vomiting |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D007792 | Lactulose |
| ID | Term |
|---|---|
| D004187 | Disaccharides |
| D009844 | Oligosaccharides |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
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Frequency of nausea and vomiting between lactulose and non-lactulose groups post Caesarean Section. |
| First 5 days post-Caesarean |
| D009461 | Neurologic Manifestations |
| D000073893 |
| Sugars |