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Chemerin is a novel adipokine that might provide a link between chronic inflammation and obesity. Pulse wave velocity(PWV) is a useful method for examining arterial stiffness, meaning early-stage atherosclerosis. Therefore, in the present study, the investigators examined the relationship between circulating chemerin and arterial stiffness measured using PWV in obese persons.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non- obese group | |||
| Obese group |
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| Measure | Description | Time Frame |
|---|---|---|
| The difference of serum chemerin level between obese and non-obese groups | serum chemerin levels of all participants were by determined by an enzyme-linked immunosorbent assay (ELISA) kit (Biovender Laboratory Medicine Inc., Modrice, Czech Republic) | at the time of initial enrollment (4weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| The correlation of serum chemerin levels with arterial stiffness | Arterial stiffness was measure using a Colin Waveform Analyser (model BP-203RPE II; Colin, Komaki, Japan). It was expressed as branchial ankle pulswe wave velocity (baPWV) | at the time of enrollment (4 weeks) |
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Inclusion Criteria:
Exclusion Criteria:
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Obese and age, gender matched non-obese group who underwent a medical health check in the Korea University Guro hospital
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hye Jin Yoo | Contact | 82226263045 | deisy21@naver.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hye Jin Yoo | Recruiting | Seoul | South Korea |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D050197 | Atherosclerosis |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |