This is a study to compare the safety and efficacy of the use of a intravaginal ovule containing a combination of Ketoconazole and Clindamycin to the use of an intravaginal cream containing a combination Tetracycline and Amphotericin B for the treatment of bacterial vaginosis and/or mixed or isolated vaginal candidiasis.

Inclusion Criteria:

• Diagnosis of vaginal candidiasis
• No Trichomonas vaginalis or any other protozoa
• No clinical evidences of infection by Neisseria gonorrhoeae, Chlamydia trachomatis, or viral infections

Exclusion Criteria:

• Known sensitivity to the formula components
• Pregnant or nursing patients
• Any gynecological condition contraindicating the use of vaginal ovule or cream.
• Use of any other local or systemic bactericidal, anti-protozoa or antifungal agent within the 2 weeks prior to the study start or during it
• Presence of other sexually transmitted diseases (except from Candidal vaginitis).
• History of recurrent candidiasis (≥4 episodes per year)
• Use of intra-uterine device, spermicides, or diaphragms
• Has metabolic or immune disorder
• Has abnormal uterine bleeding