Triclosan containing dentifrices are effective in the prevention of inflammatory complications following third molar surgery through reducing preoperative oral bacteria load.

This study may provide evidence on the effect of triclosan containing dentifrice on oral bacteria and oral inflammation prior to third molar surgery, and on the incidence of inflammatory complications after the surgery. If proven effective, dentifrice containing triclosan may be recommended prior to tooth extractions and replace antibiotics and other antimicrobial products as a prophylactic procedure before oral surgery procedures.

Inclusion Criteria:

• must include at least one mandibular third molar with partial or full bony impaction
• no sign of active pericoronal (around the crown) infections
• must have not taken antibiotics for any reason in the past 30 days
• must be healthy and between 18 and 35 years of age
• must be able to read and sign an informed consent

Exclusion Criteria:

• Subjects with systemic diseases and pregnant or lactating women
• Subjects with advanced periodontal diseases or having two or more untreated caries lesions
• Subjects who cannot read and sign an informed consent
• Subjects with signs of pericoronal infections