Insulin Balanced Infusion System

Insulin Balanced Infusion System Control of Glucose

The purpose of this study is to study the use of a counterbalancing system of glucose and insulin infusion with frequent blood glucose monitoring and combined adaptive algorithm can produce tight glycemic control without hypoglycemia; study to develop a closed loop for use in intensive care units and surgery

The study is using an experimental design outpatient with individuals having treatment using an automated closed loop glucose control unit; glucoses are measured every 5 minutes using a intravenous glucose sensor and infusion of glucose and insulin are altered without manual intervention as directed by algorithm

Inclusion Criteria:

• type 1 or type 2 diabetic individuals on insulin ages 21-85 with A1c 7-9.9%
• glucose at time of study > 150 mg/dl

Exclusion Criteria:

• pregnancy
• renal or hepatic disease
• corticosteroids
• poor intravenous access
• anemia
• electrolyte abnormality