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The purpose of this study is to investigate the effect of platelet infusion prior to transfer to a vascular surgical department in patients with a ruptured abdominal aortic aneurism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control treatment | No Intervention | Usual transfusion regime to patients with rAAA | |
| Thrombocyte | Experimental | Early thrombocyte administration to patients with rAAA |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Platelet | Procedure | 2 portions of platelets (one portion = pooled from 4 donors, 350ml) infused when diagnosed with rAAA and vascular surgeon accepts to receive the patient, infused before transportation. |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Mortality during the first 30days after randomization, and time to death during the 30 days. | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Acute myocardial infarction | Development of AMI during the first 30 days after randomization, and the time to development during the first 30 days. | 30 days |
| Post operative kidney failure | The need for dialysis during the first 30 days, time to start of dialysis and length. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Thomas Bech Jørgensen, MD | Contact | 25620901 | starttrial@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Henning Bay Nielsen, MD | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rigshospitalet | Recruiting | Copenhagen | Oesterbro | 2100 | Denmark |
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| ID | Term |
|---|---|
| D020141 | Hemostatic Disorders |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006474 | Hemorrhagic Disorders |
| D006402 | Hematologic Diseases |
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| ID | Term |
|---|---|
| D010976 | Platelet Count |
| ID | Term |
|---|---|
| D001772 | Blood Cell Count |
| D002452 | Cell Count |
| D003584 | Cytological Techniques |
| D019411 | Clinical Laboratory Techniques |
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|
| 30 days |
| Post operative pulmonary insufficiency | Length of respirator treatment in the ICU during the first 30 days. | 30 days |
| Length of stay in ICU | Length of stay in ICU | until discharged from ICU |
| Length of stay in hospital | Until discharged from main surgical department or if transferred to local hospital, when the patient leave local hospital. | until discharged from hospital |
| D006425 |
| Hemic and Lymphatic Diseases |
| D019937 |
| Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D006403 | Hematologic Tests |
| D010979 | Platelet Function Tests |
| D008919 | Investigative Techniques |
| D002468 | Cell Physiological Phenomena |
| D001790 | Blood Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |