HCV and HIV viral load pre and post antiretroviral therapy (ART). ART is the intervention and the comparison is the HIV and HCV viral load reductions as determined by RT-PCR after administration of interferon alfa in each instance (before and after ART)

Peginterferon alfa-2b administered once as part of a pharmacokinetic study before and after anti-HIV medications. Peginterferon is used to produce a measurement but the intervention is the HIV medications which are specified as raltegravir, emtricitabline, and tenofovir disoproxil fumerate.

HCV RNA determined by reverse transcription polymerase chain reaction and measured as log IU/ml 48 hours after a single dose of peginterferon alfa 2b 1.5 μg/kg.

HCV and HIV viral load pre and post antiretroviral therapy

Anti-HIV Agents: Interferon alfa-2b administered once as part of a pharmacokinetic study before and after anti-HIV medications.

raltegravir: HIV medication, 400 mg twice daily by mouth

Emtricitabine and tenofovir disoproxil fumarate: HIV medication, combination pill, once per day by mouth

HCV RNA determined by reverse transcription polymerase chain reaction and measured as log IU/ml 48 hours after a single dose of peginterferon alfa 2b 1.5 μg/kg.

HCV and HIV viral load pre and post antiretroviral therapy

Anti-HIV Agents: Interferon alfa-2b administered once as part of a pharmacokinetic study before and after anti-HIV medications.

raltegravir: HIV medication, 400 mg twice daily by mouth

Emtricitabine and tenofovir disoproxil fumarate: HIV medication, combination pill, once per day by mouth

As an expected potential complication of liver biopsy, one patient had bleeding that required observation in the hospital. No residual complications were noted.