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Non-invasive ventilation (NIV) has been proposed to reduce the incidence of ventilatory dysfunction following mechanical ventilation weaning. However, the nasogastric tube reduces the airtightness of the facial mask used to perform non-invasive ventilation and induces air leaks. The presence of leaks at the patient-mask interface can increase the risk of patient-ventilator asynchrony, which in turn leads to increase patient discomfort. Neurally adjusted ventilatory assist (NAVA)could contribute to decreasing asynchrony. Its principle is to record the diaphragmatic electrical activity and to control the ventilator. The investigators hypothesized driving the ventilator based on a neural signal (diaphragm electrical activity) would reduce patient-ventilator asynchronies in NIV
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non invasive ventilation | Non-invasive ventilation after invasive mechanical ventilation weaning |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Device: Neurally Adjusted Ventilatory Assistance | Other | Device: Neurally Adjusted Ventilatory Assistance In ICU following extubation NIV was performed as follows: facial mask with PSV/NIV mode to define settings for NAVA ventilation facial use with NAVA/NIV mode |
| Measure | Description | Time Frame |
|---|---|---|
| Triggering delay | Duration between the onset of neural inspiration and the onset of insufflation | Every inspiration, for 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Cycling off delay | Delay between the end of neural inspiration and the end of insufflation | Every inspiration, for 10 minutes |
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Inclusion Criteria:
Patients with increased risk of post-extubation ventilatory dysfunction following invasive mechanical ventilation weaning.
Exclusion Criteria:
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NIV required on post extubation period
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Groupe Hospitalier Pitié Salpétrière, Department of intensive care and pneumology | Paris | 75013 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22610179 | Derived | Schmidt M, Dres M, Raux M, Deslandes-Boutmy E, Kindler F, Mayaux J, Similowski T, Demoule A. Neurally adjusted ventilatory assist improves patient-ventilator interaction during postextubation prophylactic noninvasive ventilation. Crit Care Med. 2012 Jun;40(6):1738-44. doi: 10.1097/CCM.0b013e3182451f77. |
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