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| Name | Class |
|---|---|
| Insel Gruppe AG, University Hospital Bern | OTHER |
| Kantonsspital Baden | OTHER |
| University of Zurich | OTHER |
| Luzerner Kantonsspital |
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Until now, no risk assessment model informing about the need of thromboprophylaxis in patients admitted for an acute medical event has been validated.
The goal of this project is to indirectly validate a model developed in Geneva by a non -interventional study involving the collection of patient characteristics during the hospitalization and a 3-month follow-up. These data will allow for the determination of the patient's risk, according to the Geneva model, and its validity, according the actual thrombo-embolic events, corrected for the thromboprophylaxis received.
The project is multicentric in Switzerland (5-10 centers) and should involve about 1000 patients.
First amendment (may 2011) : we have obtained the IRB approval for collecting data from patients who die during their hospital stay and for whom informed consent is not be possible to obtain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| hospitalization >24 hours |
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| Measure | Description | Time Frame |
|---|---|---|
| relationship between the combined rate of fatal and non-fatal symptomatic venous thromboembolism and bleeding events and the calculated risk score at 90 days after hospital admission | evaluation of the relationship between the combined rate of fatal and non-fatal symptomatic venous thromboembolism and bleeding events at 90 days after hospital admission on one hand, and the calculated risk score provided by the Geneva Risk Assessment Models (RAM) at hospital admission on the other hand | 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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Several public hospitals of Switzerland, genral internal medicine divisions
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| Name | Affiliation | Role |
|---|---|---|
| Mathieu R Nendaz, Dr | General Internal Medicine Division, University Hospitals of Geneva | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kantonsspital | Baden | Switzerland | ||||
| University Hospitals |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16634771 | Background | Chopard P, Spirk D, Bounameaux H. Identifying acutely ill medical patients requiring thromboprophylaxis. J Thromb Haemost. 2006 Apr;4(4):915-6. doi: 10.1111/j.1538-7836.2006.01818.x. No abstract available. | |
| 24226257 | Result | Nendaz M, Spirk D, Kucher N, Aujesky D, Hayoz D, Beer JH, Husmann M, Frauchiger B, Korte W, Wuillemin WA, Jager K, Righini M, Bounameaux H. Multicentre validation of the Geneva Risk Score for hospitalised medical patients at risk of venous thromboembolism. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thromb Haemost. 2014 Mar 3;111(3):531-8. doi: 10.1160/TH13-05-0427. Epub 2013 Nov 14. |
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| ID | Term |
|---|---|
| D054556 | Venous Thromboembolism |
| ID | Term |
|---|---|
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| OTHER |
| Cantonal Hospital of St. Gallen | OTHER |
| Sanofi | INDUSTRY |
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| Bern |
| Switzerland |
| Cantonal Hospital | Fribourg | Switzerland |
| University Hospitals | Geneva | Switzerland |
| Kantonsspital | Lüzern | Switzerland |
| Cantonal Hospital | Sankt Gallen | Switzerland |
| University Hospital | Zurich | Switzerland |
| 25608607 | Derived | Spirk D, Nendaz M, Aujesky D, Hayoz D, Beer JH, Husmann M, Frauchiger B, Korte W, Wuillemin WA, Righini M, Bounameaux H, Kucher N. Predictors of thromboprophylaxis in hospitalised medical patients. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thromb Haemost. 2015 May;113(5):1127-34. doi: 10.1160/TH14-06-0525. Epub 2015 Jan 22. |