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Objective: to evaluate if the Neobladder posterior wall suspended with round ligament of uterus could improve neobladder empty after radical cystectomy in female patients with bladder cancer compared to present standard neobladder
The investigators developed a technical modification which to aim to provide an posterior support to the ideal neobladder and obtain the anatomy recovered neobladder by posterior wall of neobladder suspended with round ligament. In this study the investigators designed the prospective random trial to evaluate whether this technique improves the neobladder empty compared to a current standard neobladder reconstruction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| neobladder with round lig | Experimental | ileal neobladder suspened with round ligament |
|
| standard neobladder | No Intervention | conventional standard neobladder |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| rONB | Procedure | Neobladder posterior wall suspended with round ligament of uterus after radical cystectomy in female with bladder cancer |
|
| Measure | Description | Time Frame |
|---|---|---|
| postvoiding residual urine (PVP) | number of patients with postvoiding residual urine (PVP) more than 100ml | 2 years after operation |
| clean intermittent catheterization(CIC) | number of patients required clean intermittent catheterization(CIC) | 2 years after operation |
| Measure | Description | Time Frame |
|---|---|---|
| rate of complication | number of patients with any complication | through study completion, an average of 2 years |
| urodynamic profile | urodynamic parameter including peak flow rate, functional urethral length ...etc |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| ZhiWen Chen, M.D. | Urology Institute of PLA, Southwest Hospital, Chongqin, China | Study Chair |
| HuiXiang Ji, M.D. | Urology Institute of PLA, Southwest Hospital, Chongqin, China | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Urology Institute of PLA, Southwest Hospital | Chongqing | 400038 | China |
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| ID | Term |
|---|---|
| D001749 | Urinary Bladder Neoplasms |
| ID | Term |
|---|---|
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| 12 months afer operation |
| rate of continence of neobladder | number of patients with continence at daytime and nighttime | 12 months after operation |
| D052776 |
| Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D001745 | Urinary Bladder Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |