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The purpose of this study is to determine whether the probiotic Infloran is cost-effective in treating acute childhood diarrhea.
Probiotics have been proved to shorten duration of diarrhea in children; whether they are cost-effective is less clear. We'd like to validate the use of Infloran, a proprietary probiotic sold in Thailand, in terms of its cost-effectiveness compared to standard diarrhea care in our hospital setting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | The group of patients treated with placebo. |
|
| Infloran | Experimental | The group of patients treated with Infloran. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotic - Infloran | Drug | Drug:Probiotic - Infloran (TM) 1 cap (1 billion CFU of L. acidophilus and 1 billion CFU of B. bifidum) PO bid or tid |
|
| Measure | Description | Time Frame |
|---|---|---|
| monetary cost of hospitalization in Thai Baht | from admission to discharge date, approximately 1-7 days |
| Measure | Description | Time Frame |
|---|---|---|
| days of hospitalization | from admission to discharge date, approximately 1-7 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nopaorn Phavichitr, MD | Department of Pediatrics, Phramongkutklao | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Pediatrics, Phramongkutklao Hospital | Recruiting | Bangkok | 10400 | Thailand |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Sep 28, 2012 | |
| Reset | Oct 29, 2012 | |
| Release | Oct 29, 2012 | |
| Unrelease | Yes | |
| Release | Oct 30, 2012 | |
| Reset | Nov 27, 2012 | |
| Release | Nov 29, 2012 | |
| Reset | Dec 28, 2012 | |
| Release | Jan 2, 2013 | |
| Reset | Feb 4, 2013 | |
| Release | Feb 4, 2013 | |
| Unrelease | Yes | |
| Release | Mar 7, 2013 | |
| Reset | Apr 12, 2013 | |
| Release | Nov 14, 2013 | |
| Reset | Jan 6, 2014 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Sep 28, 2012 | Oct 29, 2012 | |||
| Oct 29, 2012 |
| ID | Term |
|---|---|
| D003967 | Diarrhea |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| C504214 | acidocin D20079, Lactobacillus acidophilus |
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|
| Yes |
| Oct 30, 2012 | Nov 27, 2012 |
| Nov 29, 2012 | Dec 28, 2012 |
| Jan 2, 2013 | Feb 4, 2013 |
| Feb 4, 2013 | Yes |
| Mar 7, 2013 | Apr 12, 2013 |
| Nov 14, 2013 | Jan 6, 2014 |