Characterization and Evaluation of Diagnostic Biomarkers for Tuberculosis

Characterization and Evaluation of Diagnostic Biomarkers for Tuberculosis

There was no sensitive and specific biomarker for tuberculosis infection, disease progression and predicting the prognosis of treatment. Therefore, the investigators aimed to investigate and evaluate the newer biomarker for the diagnosis of TB infection. To investigate the new biomarker for TB infection, the investigators will recruit the participants including active TB patients, healthy household contacts, healthy community control.

Inclusion Criteria:

• active TB patients : diagnosed with active TB through the microbiologic examination, imaging findings
• healthy control : no history of TB treatment, no respiratory symptoms, no evidence of active infectious disease including TB on chest X-ray, no history of close contacts of active pulmonary TB patients

Exclusion Criteria:

• pregnant woman
• positive result of human immunodeficiency virus examination