Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Bronchiectasis can be defined as an abnormal and irreversible dilatation of the bronchial tree due to repeated cycles of inflammation and infection, resulting in progressive loss of lung function. The surgical treatment by pulmonary resection or even lung transplantation is indicated in cases of bronchiectasis primary nonresponsive to appropriate medical treatment, or when associated with serious complications. There are few literature data on the influence of bronchiectasis in exercise capacity, quality of life and functional capacity, and the impact of lung resection in patients with this diagnosis. The primary objective of this study is to evaluate prospectively the impact of lung resection on exercise capacity in patients with clinical and radiological diagnosis of bronchiectasis. The secondary objective of this study is to evaluate the impact of lung resection on quality of life and lung function and to analyze the the presence of predictors of postoperative functional deterioration and the occurrence of complications.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Impact of Pulmonary Resection on Exercise Capacity | Exercise Capacity will be assessed using Cardiopulmonary Exercise Test. | Change from Baseline in Exercise Capacity at 3 months and Change from Baseline in Exercise Capacity at 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Impact of Pulmonary Resection on Quality of Life. | Quality of life will be assessed using WHOQOL-Bref and SF-36 questionnaries. | Change from Baseline in Quality of Life at 3 months and Change from Baseline in Quality of Life at 9 months. |
| Impact of Pulmonary Resection on Lung Function. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Patients with clinical and radiological diagnosis of bronchiectasis recruited on Pulmonary Suppurative Disease Clinic of Thoracic Surgery Department
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ricardo Mingarini Terra, MD, PhD | Contact | 55 11 3069597 | rmterra@uol.com.br |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Sao Paulo Medical School - Heart Institute | Recruiting | São Paulo | São Paulo | 05403-000 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33491053 | Derived | Mariani AW, Vallilo CC, de Albuquerque ALP, Salge JM, Augusto MC, Suesada MM, Pego-Fernandes PM, Terra RM. Preoperative evaluation for lung resection in patients with bronchiectasis: should we rely on standard lung function evaluation? Eur J Cardiothorac Surg. 2021 Jun 14;59(6):1272-1278. doi: 10.1093/ejcts/ezaa454. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001987 | Bronchiectasis |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Lung Function will be assessed using Spirometry Test. |
| Change from Baseline in Lung Function at 3 months and Change from Baseline in Lung Function at 9 months. |